NIOME

Clone the NIOME subnet repository

git clone https://github.com/genomesio/subnet-niome.git && cd subnet-niome

Create and activate Python virtual environment

python3 -m venv venv && source venv/bin/activate

Install required Python packages

python3 -m pip install -r requirements.txt

Install Bittensor CLI for wallet management

python3 -m pip install bittensor-cli

Create coldkey (primary wallet for storing TAO)

btcli wallet new_coldkey --wallet.name your_coldkey

Create hotkey (miner identity for signing transactions)

btcli wallet new_hotkey --wallet.name your_coldkey --wallet.hotkey your_hotkey

Register hotkey to NIOME subnet (netuid 55) to obtain UID

btcli subnet register --netuid 55 --wallet.name your_coldkey --wallet.hotkey your_hotkey

Set Python path for project execution

export PYTHONPATH="$PYTHONPATH:$(pwd)"

Launch miner neuron (requires specifying port)

python neurons/miner.py --netuid 55 --subtensor.network finney --wallet.name your_coldkey --wallet.hotkey your_hotkey --axon.port your_port

Use pm2 or tmux to keep miner running persistently (validators reward only active, responsive miners)(optional)

pm2 start neurons/miner.py --name niome_miner -- --netuid 55 --subtensor.network finney --wallet.name your_coldkey --wallet.hotkey your_hotkey --axon.port your_port

Clone the NIOME subnet repository

git clone https://github.com/genomesio/subnet-niome.git && cd subnet-niome

Create and activate Python virtual environment

python3 -m venv venv && source venv/bin/activate

Install required Python packages

python3 -m pip install -r requirements.txt

Set up Docker repository

sudo apt-get update && sudo apt-get install -y ca-certificates curl gnupg && sudo install -m 0755 -d /etc/apt/keyrings && curl -fsSL https://download.docker.com/linux/ubuntu/gpg | sudo gpg --dearmor -o /etc/apt/keyrings/docker.gpg

Add Docker APT source

echo "deb [arch=$(dpkg --print-architecture) signed-by=/etc/apt/keyrings/docker.gpg] https://download.docker.com/linux/ubuntu $(. /etc/os-release && echo $VERSION_CODENAME) stable" | sudo tee /etc/apt/sources.list.d/docker.list > /dev/null

Install Docker packages

sudo apt-get update && sudo apt-get install -y docker-ce docker-ce-cli containerd.io docker-buildx-plugin docker-compose-plugin

Verify Docker installation

docker run --rm hello-world

Create coldkey and hotkey for validator registration

btcli wallet new_coldkey --wallet.name your_coldkey && btcli wallet new_hotkey --wallet.name your_coldkey --wallet.hotkey your_hotkey

Register validator hotkey to subnet 55

btcli subnet register --netuid 55 --wallet.name your_coldkey --wallet.hotkey your_hotkey

Make validator entrypoint script executable

chmod +x entrypoint.sh

Run validator interactively (prompts for wallet.name, wallet.hotkey, optionally wandb.api_key; sets up venv, installs dependencies, installs system tools (bwa, samtools, tabix, bcftools), starts validator as PM2 process, enables auto-restart on git updates)

./entrypoint.sh