Overview
Registration Activity
Neuron registration trends
Neuron registration trends
The alpha price in τ, day by day, and what moved it each way.
Log change over the last 30 days −34.06%: protocol buys +26.36%, root sells −5.53%, users net −62.71%, cross-subnet +7.83%, unattributed +0.0001%.
The chart follows the alpha price in τ. Each period starts at its opening price and steps through the mechanisms below, in a fixed order, to its closing price: a step that rises pushed the price up, one that falls pushed it down, and its height is how far it moved the price. A thin line carries each close into the next period’s open; it is dashed where the two differ. The faint candle behind each period is the market’s own open, high, low and close, for context.
With many periods on screen (90 days, or hours), the steps would be too thin to read, so the chart draws the price as a line instead and colours each period by the mechanism that moved it most. Hover a period for the full step-by-step breakdown.
Not here, because they do not move the spot price: the per-block TAO injection into the pool, and burns.
All figures are log changes, not simple percentage changes, so the parts add up exactly to the total; on big moves the two differ (a 10% log fall is a 9.5% price fall).
2026-11-07 UTC, as of ≈16:16 UTC (block 9,455,373)
The day isn’t over yet, so these figures keep changing. They are in no daily total, average or rank.
Variant calling—predicting genetic differences from sequencing data—is computationally intensive and sensitive to tool configuration. Existing deployments centralize calling and validation, limiting experiment scope and reproducibility. No decentralized mechanism currently rewards miners for accurate calls or validates results at scale.
Minos addresses this with a network of independent miners that submit variant-calling configurations and run them on challenge genomic data. Each miner competes on the accuracy of their calls (measured by SNP/indel F1, precision, and recall) without requiring a central authority to certify results. Validators re-run each miner's configuration locally to verify correctness, score the output using hap.py benchmarking against ground-truth variant data, and aggregated scores determine miner weight and TAO emissions.
On Bittensor subnet 107, miners run GATK HaplotypeCaller, DeepVariant, or BCFtools on platform-provided BAM files and reference genomes. Validators independently score each submission using identical hap.py protocols and network-pinned scoring versions (v1 or v2 formulas).
Platform coordinates round timing, presigned file URLs, truth data, and backfill scoring for gap coverage. Weights reflect each miner's combined performance (eligibility, recent scores, rank distribution) under a public protocol that prevents collusion and dust attacks.
Auto-generated from the GitHub repository and may not reflect the latest changes.
Minos (Subnet 107) is a Bittensor subnet for genomic variant calling that scores miners on the accuracy of their variant-calling tool outputs (GATK, DeepVariant, BCFtools) against benchmark truth data using hap.py benchmarking. Miners submit tool configurations and settings rather than VCF files; validators re-run those configs on challenge BAM files, score the resulting calls against truth VCF using hap.py, and set weights based on accuracy metrics (SNP/indel F1, precision, recall).
Minos uses a round-based platform architecture. Platform announces BAM challenge regions, presigned download URLs, and truth VCF URLs. Miners poll the platform for active rounds, download BAM + reference data, run their selected variant caller with submitted config parameters, generate a VCF, and submit the config to the platform.
Validators also poll for scoring-phase rounds, download the same BAM + truth VCF, re-run each miner's config to regenerate the VCF (to verify correctness, not trust miner output), score using hap.py benchmarking tool, and submit scores back to the platform. Scores are aggregated across validators (backfill mechanism fills gaps when some validators miss a miner). Platform records scores, eligibility windows, and participation history.
Validators read network configuration and scoring version pins from the platform, compute weight distributions based on miner scores/eligibility/participation, and set on-chain weights via Bittensor SDK. Miners earn TAO emissions based on weights; validators earn TAO through Bittensor incentive mechanism.
Miners submit variant-calling tool configurations (GATK, DeepVariant, BCFtools parameters) not VCF files. Platform distributes BAM challenge files to miners. Each miner runs their config, produces a VCF, and submits it.
Validators download the BAM + truth VCF, re-run each miner's config, score the resulting VCF using hap.py benchmarking (comparing calls to ground truth), and compute an AdvancedScore (0-100) that maps to combined_final (0-1]. Scores are validated for range, zero-input detection, and scale consistency. On-chain weights reflect miner eligibility and round-based ranking: top scorer gets winner bonus weight, lower scorers get pruning+dust allocation.
Miners earn emissions proportional to weight assigned each round.
The sections above were auto-generated from the GitHub repository and may not reflect the latest changes. View repository (github.com, opens in a new tab, external site)
The Foundational Layer of Genomics
This information was auto-extracted from the GitHub repository and may be incomplete or out of date. Always refer to the subnet's GitHub repository (github.com, opens in a new tab, external site) for the latest instructions.
Machine-extracted from the subnet's repository docs; may be wrong or out of date. Check the repository before buying or renting hardware. Open the repository (github.com, opens in a new tab, external site) · Extracted 12 Oct 2026
Install Minos miner and dependencies
bash install.sh
Run demo mode to verify your pipeline works (no chain, no wallet required; one-shot against fixed sample)
bash start-miner.sh --demo
Verify Docker is running and accessible
docker info
Run practice mode to score a config against a sample from the platform (self-scorer; no chain submission)(optional)
bash start-miner.sh --practice --config configs/gatk.conf
Create or attach Bittensor wallet and hotkey
bash start-miner.sh --setup
Register hotkey on subnet 107 (required to earn TAO)
btcli subnets register --netuid 107 --wallet.name <name> --wallet.hotkey <hotkey>
Start live miner (polls platform for rounds, submits configs)
bash start-miner.sh
Start miner under PM2 process manager for persistent operation(optional)
bash pm2-miner.sh
Install Minos validator and dependencies
bash install.sh
Verify Docker is running (required for scoring tools)
docker info
Create or attach Bittensor wallet and hotkey
bash start-validator.sh --setup
Register hotkey as validator on subnet 107 with stake
btcli subnets register --netuid 107 --wallet.name <name> --wallet.hotkey <hotkey> --stake-amount <amount>
Start validator (polls platform for scoring rounds, scores miner submissions, sets weights)
bash start-validator.sh
Start validator under PM2 for persistent operation and auto-restart(optional)
bash pm2-validator.sh
| Day (UTC) | Share |
|---|---|
| 2026-11-06 | 3.74% |
| 2026-11-05 | 3.77% |
| 2026-11-04 | 3.74% |
| 2026-11-03 | 3.58% |
| 2026-11-02 | 3.36% |
| 2026-11-01 | 3.32% |
| 2026-10-31 | 3.36% |
| 2026-10-30 | 3.31% |
| 2026-10-29 | 3.72% |
| 2026-10-28 | 4.00% |
| 2026-10-27 | 3.95% |
| 2026-10-26 | 3.99% |
| 2026-10-25 | 4.08% |
| 2026-10-24 | 4.13% |
| 2026-10-23 | 4.07% |
| 2026-10-22 | 4.04% |
| 2026-10-21 | 4.17% |
| 2026-10-20 | 4.28% |
| 2026-10-19 | 4.05% |
| 2026-10-18 | 4.15% |
| 2026-10-17 | 4.39% |
| 2026-10-16 | 4.54% |
| 2026-10-15 | 4.69% |
| 2026-10-14 | 4.72% |
| 2026-10-13 | 4.78% |
| 2026-10-12 | 4.82% |
| 2026-10-11 | 4.84% |
| 2026-10-10 | 4.65% |
| 2026-10-09 | 4.89% |
| 2026-10-08 | 5.03% |
| 2026-10-07 | 5.11% |
| 2026-10-06 | 5.20% |
| 2026-10-05 | 5.35% |
| 2026-10-04 | 5.33% |
| 2026-10-03 | 5.49% |
| 2026-10-02 | 5.57% |
| 2026-10-01 | 5.51% |
| 2026-09-30 | 5.89% |
| 2026-09-29 | 5.59% |
| 2026-09-28 | 5.44% |
| 2026-09-27 | 5.52% |
| 2026-09-26 | 5.88% |
| 2026-09-25 | 5.91% |
| 2026-09-24 | 5.65% |
| 2026-09-23 | 5.77% |
| 2026-09-22 | 6.13% |
| 2026-09-21 | 6.16% |
| 2026-09-20 | 6.22% |
| 2026-09-19 | 6.50% |
| 2026-09-18 | 6.58% |
| 2026-09-17 | 6.78% |
| 2026-09-16 | 7.03% |
| 2026-09-15 | 7.32% |
| 2026-09-14 | 7.48% |
| 2026-09-13 | 7.38% |
| 2026-09-12 | 7.49% |
| 2026-09-11 | 7.69% |
| 2026-09-10 | 7.63% |
| 2026-09-09 | 7.98% |
| 2026-09-08 | 2.52% |
| 2026-09-07 | 0.11% |
| 2026-09-06 | 0.00% |
| 2026-09-05 | 0.00% |
| 2026-09-04 | 0.00% |
| 2026-09-03 | 0.00% |
| 2026-09-02 | 0.24% |
| 2026-09-01 | 8.20% |
| 2026-08-31 | 8.17% |
| 2026-08-30 | 8.14% |
| 2026-08-29 | 8.31% |
| 2026-08-28 | 8.81% |
| 2026-08-27 | 8.69% |
| 2026-08-26 | 8.96% |
| 2026-08-25 | 9.06% |
| 2026-08-24 | 9.49% |
| 2026-08-23 | 9.84% |
| 2026-08-22 | 9.87% |
| 2026-08-21 | 9.34% |
| 2026-08-20 | 9.02% |
| 2026-08-19 | 8.85% |
| 2026-08-18 | 8.90% |
| 2026-08-17 | 8.96% |
| 2026-08-16 | 8.87% |
| 2026-08-15 | 8.34% |
| 2026-08-14 | 8.27% |
| 2026-08-13 | 8.29% |
| 2026-08-12 | 8.11% |
| 2026-08-11 | 8.85% |
| 2026-08-10 | 9.12% |
| 2026-08-09 | 9.43% |